Dosage
Use as Needed for Erectile Dysfunction : The recommended starting dose is 10 mg .The dose may be increased to 20 mg or decreased to 5 mg, based on individual efficacy and tolerability ; For Once Daily Use for Erectile Dysfunction : The recommended starting dose for once daily use is 2.5 mg, taken at approximately the same time every day . The dose for once daily use may be increased to 5 mg , based on individual efficacy and tolerability ; For Once Daily Use for Benign Prostatic Hyperplasia : The recommended dose for once daily use is 5 mg, taken at approximately the same time every day ; For Once Daily Use for Erectile Dysfunction and Benign Prostatic Hyperplasia : The recommended dose for once daily use is 5 mg . Or As directed by your physician.
Side Effects
Body as a Whole : Asthenia, face edema, fatigue, pain ; Cardiovascular : Angina pectoris, chest pain, hypotension, myocardial infarction, postural hypotension, palpitations, syncope, tachycardia ; Digestive : Abnormal liver function tests, dry mouth, dysphagia, esophagitis, gastritis, GGTP increased, loose stools, nausea, upper abdominal pain, vomiting, gastroesophageal reflux disease, hemorrhoidal hemorrhage, rectal hemorrhage ; Musculoskeletal : Arthralgia, neck pain ; Nervous : Dizziness, hypesthesia, insomnia, paresthesia, somnolence, vertigo ; Renal and Urinary : Renal impairment ; Respiratory : Dyspnea, epistaxis, pharyngitis ; Skin and Appendages : Pruritus, rash, sweating ; Ophthalmologic : Blurred vision, changes in color vision, conjunctivitis (including conjunctival hyperemia), eye pain, lacrimation increase, swelling of eyelids ; Otologic : Sudden decrease or loss of hearing, tinnitus ; Urogenital : Erection increased, spontaneous penile erection .
Drug Interactions
An alpha blocker (used to treat high blood pressure or urinary symptoms associated with benign prostatic hyperplasia) , other medicines to treat high blood pressure , riociguat , a 5- alpha reductase inhibitor (used to treat benign prostatic hyperplasia) , medicines such as ketoconazole tablets (to treat fungal infections) and protease inhibitors for treatment of AIDS or HIV infection , phenobarbital, phenytoin and carbamazepine (anticonvulsant medicines) , rifampicin, erythromycin , clarithromycin or itraconazole , other treatments for erectile dysfunction.
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