Description
Zolp Tablets 10mg (1 Strip = 10 Tablets) Specification
Requires Prescription (YES/NO)
Yes
Generics
Zolpidem Tartrate
Used For
Insomnia
How it works
Zolpidem is an imidazopyridine which selectively binds the omega-1 receptor subtype (also known as the benzodiazepine-1 subtype) which is the alpha unit of the GABA-A receptor complex. Whereas benzodiazepines non-selectively bind all three omega receptor subtypes, zolpidem preferentially binds the omega-1 subtype. The modulation of the chloride anion channel via this receptor leads to the specific sedative effects demonstrated by zolpidem. These effects are reversed by the benzodiazepine antagonist flumazenil.
Usage And Safety
Dosage
Adults : 10mg before sleeping. Elderly : 5mg before sleeping. Children : Not recommended or as directed by your physician.
Side Effects
Memory disorders such as poor memory (amnesia), memory impairment, anterograde amnesia , hallucinations ; Drowsiness or a strong desire to sleep ; Dizziness ; Diarrhoea ; Feeling sick (nausea) or being sick (vomiting) ; Abdominal pain ; Infection of the lungs or airways (respiratory infection) ; Headache ; Feeling tired or agitated ; Nightmares ; Depression ; Back pain.
Drug Interactions
Antipsychotics , sertraline , narcotic analgesics , anticonvulsants , anaesthetics , hypnotics , sedative antihistamines such as chlorphenamine or promethazine , antidepressants including bupropion, desipramine, fluoxetine, sertraline and venlafaxine.
Indication
It is used for short-term treatment of insomnia in patients over 18 years of age, that is causing you severe distress or that is affecting your everyday life.
When not to Use
Do not use if you are allergic (hypersensitive) to zolpidem tartrate or any of the other ingredients of this medicine ; As a long-term treatment. Treatment should be as short as possible, because the risk of dependence increases with the duration of treatment ; If you have ever experienced sleep walking or other behaviours which are unusual while sleeping (such as driving, eating, making a phone call or having sex etc.) while not being fully awake after taking zolpidem tartrate tablets or other medicines containing zolpidem .
Precautions
Precaution
Concomitant use of zolpidem and opioids may result in sedation, respiratory depression, coma and death. Because of these risks, concomitant prescribing of sedative medicines such as benzodiazepines or related drugs such as zolpidem with opioids should be reserved for patients for whom alternative treatment options are not possible.
Warnings
Warning 1
Hypnotics such as zolpidem are not recommended for the primary treatment of psychotic illness.
Warning 2
Use of zolpidem may lead to the development of abuse and/or physical and psychological dependence. The risk of dependence increases with dose and duration of treatment. Cases of dependence have been reported more frequently in patients treated with zolpidem for longer than 4 weeks. The risk of abuse and dependence is also greater in patients with a history of psychiatric disorders and/or alcohol, substance or drug abuse. Zolpidem should be used with extreme caution in patients with current or a history of alcohol, substance or drug abuse or dependence.
Warning 3
Due to its pharmacological properties, zolpidem can cause drowsiness and a decreased level of consciousness, which may lead to falls and consequently to severe injuries.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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